HELSINKI, March 10, 2023 – Lipidomics Consulting Ltd, a front-running lipidomics company that is fundamentally changing how understanding the mechanistic and metabolic details of lipids are investigated in disease, together with scientists at University of Wollongong (UoW) and Aspect Analytics NV have received a grant

Matrix-assisted laser desorption ionization–mass spectrometry imaging (MALDI-MSI) is an emerging label-free method for mapping the distribution of diverse molecular species in tissue sections. Despite recent progress in MALDI-MSI analyses of lipids, it is still difficult to visualize minor bioactive lipids including lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P).

Defects in sphingolipid metabolism have emerged as a common link across neurodegenerative disorders, and a deeper understanding of the lipid content in preclinical models and patient specimens offers opportunities for development of new therapeutic targets and biomarkers.

Smoking is an important risk factor for the development of chronic obstructive pulmonary disease and cardiovascular diseases. This study aimed to further elucidate the role of ceramides, as a key lipid class dysregulated in disease states.